| Time | Date | Name | Meet |
|---|---|---|---|
| 50.32 | March 18, 2017 | Lindsay Hagmann | NCAA Division III Championships |
| 50.48 | Feb. 11, 2017 | Lindsay Hagmann | Southern Collegiate Athletic Conference Championships |
| 50.79 | March 19, 2016 | Lindsay Hagmann | NCAA Division III Championships |
| 50.86 | Feb. 13, 2016 | Lindsay Hagmann | Southern Collegiate Athletic Conference Championships |
| 51.14 | Feb. 14, 2015 | Lydia Jones | Southern Collegiate Athletic Conference Championships |
| 52.07 | Nov. 22, 2014 | Lydia Jones | Claremont vs. Trinity (TX) |
| 52.18 | Feb. 16, 2013 | Ana Price | Southern Collegiate Athletic Conference Championships |
| 52.78 | March 15, 2008 | Leta Gatton | NCAA Division III Womens Championship |
| 53.85 | March 11, 2006 | Lindsay Weigley | NCAA Division III Womens Championships |
