| Time | Date | Name | Meet |
|---|---|---|---|
| 51.74 | Feb. 26, 2021 | Valdas Abaliksta | Atlantic Coast Conference Men's Championships |
| 52.00 | Feb. 28, 2020 | Valdas Abaliksta | Atlantic Coast Championships (M) |
| 52.42 | March 5, 2017 | Craig Emslie | Ohio State Last Chance Meet (Men) |
| 52.73 | March 1, 2017 | Craig Emslie | Atlantic Coast Championships (M) |
| 53.24 | Feb. 27, 2015 | Kurt Wolhrab | Atlantic Coast Championships (M) |
| 53.42 | Feb. 28, 2014 | Kurt Wolhrab | Atlantic Coast Conference Championships (M) |
| 54.15 | Nov. 19, 2010 | Colin Bridier | Nike Cup (North Carolina) |
| 54.25 | Feb. 26, 2010 | Vinny Pryor | Atlantic Coast Conference Men's Championships |
| 54.35 | Feb. 27, 2009 | Vinny Pryor | Atlantic Coast Conference Championships (Men) - Day Three - Prelims |
| 55.13 | Oct. 15, 2008 | Brad Mitchell | Georgia @North Carolina |
