| Time | Date | Name | Meet |
|---|---|---|---|
| 4:21.86 | March 20, 2024 | Sam Dienstag | NCAA Division III Championship |
| 4:25.83 | Feb. 15, 2024 | Sam Dienstag | University Athletic Association Championships |
| 4:26.13 | Feb. 9, 2023 | Sam Dienstag | University Athletic Association Championships |
| 4:26.99 | Dec. 2, 2022 | Sam Dienstag | Gompei Invitational |
| 4:30.95 | Feb. 10, 2022 | Sam Dienstag | University Athletic Association Championships |
| 4:32.87 | Dec. 3, 2021 | Sam Dienstag | Gompei Invitational |
| 4:32.94 | April 2, 2021 | Sam Dienstag | Brandeis vs Bentley |
| 4:36.08 | Feb. 13, 2020 | Daniel Wohl | University Athletic Association Championships |
| 4:36.85 | Feb. 14, 2019 | Daniel Wohl | University Athletic Association Championships |
| 4:41.68 | Feb. 12, 2015 | Max Fabian | University Athletic Association Championships |
| 4:42.76 | Feb. 14, 2014 | Max Fabian | University Athletic Association Championships |
| 4:44.39 | Feb. 18, 2010 | Aaron Bennett | University Athletic Association Championships |
| 4:46.00 | Feb. 27, 2009 | Robert Morse | ECAC Open Swimming & Divi |
