| Time | Date | Name | Meet |
|---|---|---|---|
| 26.35 | Feb. 15, 2019 | Claire XU | University Athletic Association Championships |
| 27.18 | Dec. 1, 2018 | Claire XU | WPI Gompei Invitational |
| 27.66 | Nov. 30, 2018 | Claire XU | WPI Gompei Invitational |
| 27.76 | Feb. 16, 2018 | Amy Sheinhait | University Athletic Association Championships |
| 28.03 | Feb. 19, 2016 | Amy Sheinhait | University Athletic Association Championships |
| 28.50 | Feb. 13, 2015 | Amy Sheinhait | University Athletic Association Championships |
| 28.77 | Feb. 15, 2013 | Lauren Cruz | University Athletic Association Championships |
| 29.07 | Feb. 19, 2010 | Angela Chui | University Athletic Association Championships |
| 29.17 | Oct. 24, 2009 | Angela Chui | Brandies vs. Keene State |
