| Time | Date | Name | Meet |
|---|---|---|---|
| 51.10 | Feb. 17, 2019 | Caroline Murphy | NESCAC Womens Championships |
| 51.29 | March 24, 2018 | Zoe Kerrich | NCAA Division III Championships |
| 51.93 | Feb. 25, 2018 | Zoe Kerrich | NESCAC Womens Last Chance Meet |
| 52.06 | Feb. 12, 2017 | Zoe Kerrich | NESCAC Women's Championships |
| 52.26 | Feb. 14, 2016 | Zoe Kerrich | NESCAC Women's Championships |
| 52.82 | Feb. 20, 2011 | Cara Colker-Eybel | New England Small College Athletic Conference Womens Championships |
| 52.88 | Feb. 27, 2010 | Cara Madden | Last Chance Meet: NYU |
| 53.23 | Feb. 22, 2009 | Janine Zaltsman | New England Small College Athletic Conference Championships (Women) - Day Three - Finals |
| 54.95 | Nov. 22, 2008 | Janine Zaltsman | Wesleyan, Bates @Trinity (CT) |
