| Time | Date | Name | Meet |
|---|---|---|---|
| 3:20.41 | Feb. 15, 2020 | Nutter, Morrison, Hopkins, Kustritz | North Coast Athletic Conference Championships |
| 3:21.49 | March 21, 2015 | Jurjus, Kane, Yearwood, Van Leuven | NCAA Division III Championships |
| 3:21.97 | March 21, 2009 | Zaleski, Novinger, Rich, Hohl | NCAA Division III Championships |
| 3:26.06 | Nov. 8, 2008 | Kenyon @Denison | |
| 3:26.48 | March 15, 2008 | Hohl, Zaleski, Rich, Novinger | NCAA Division III Womens Championship |
| 3:28.94 | March 10, 2007 | Zaleski, Faingold, Novinger, Hohl | NCAA Division III Womens Championships |
| 3:31.23 | March 11, 2006 | Hohl, Klippel, Novinger, Dain | NCAA Division III Womens Championships |
