| Time | Date | Name | Meet |
|---|---|---|---|
| 47.94 | Feb. 10, 2024 | Cael Long | Old Dominion Athletic Conference Championships |
| 48.30 | Feb. 13, 2022 | A'Jay West | Old Dominion Athletic Conference Championships |
| 49.08 | Dec. 4, 2021 | A'Jay West | TYR Yellow Jacket Invitational |
| 49.28 | Feb. 9, 2020 | Caleb Royce | Old Dominion Athletic Conference Championships |
| 49.47 | Nov. 24, 2019 | Tyler Strong | Randolph-Macon/Yellow Jacket Invitational |
| 50.59 | Feb. 11, 2018 | Kristian Rinkus | Old Dominion Athletic Conference Championships |
| 51.66 | Dec. 3, 2017 | Kristian Rinkus | Washington & Lee Invitational |
| 52.08 | Nov. 4, 2017 | Kristian Rinkus | Virginia Wesleyan vs. Roanoke |
| 57.86 | Oct. 21, 2017 | Kyle Woolf | Virginia Wesleyan vs. Randolph |
| 1:00.32 | Oct. 14, 2017 | Austin DeRosa | ODAC Relays |
