| Time | Date | Name | Meet |
|---|---|---|---|
| 4:11.11 | March 28, 2024 | Jack Hoagland | NCAA Division I Mens Championships |
| 4:15.61 | Feb. 21, 2024 | Jack Hoagland | ASUN Championships |
| 4:15.69 | Feb. 9, 2024 | Jack Hoagland | SMU vs. Texas |
| 4:17.66 | Oct. 20, 2023 | Jack Hoagland | SMU vs. Minnesota |
| 4:17.68 | Feb. 16, 2017 | Jonathan Gomez | American Conference Championships |
| 4:18.23 | Feb. 19, 2015 | Christian Scherübl | American Conference Championships |
| 4:20.99 | March 27, 2008 | Nate Clark | NCAA Division I Mens Championships |
