| Time | Date | Name | Meet |
|---|---|---|---|
| 2:57.12 | Feb. 24, 2024 | Kiefer, Shepston, Eastham, Quigg | Atlantic 10 Championships |
| 2:59.08 | Feb. 18, 2023 | Kiefer, Montori, Eastham, Quigg | Atlantic 10 Conference Championships |
| 2:59.58 | Feb. 20, 2016 | Stiles, Wright, Gray, Karpinski | Atlantic 10 Conference Championships |
| 3:00.57 | Feb. 23, 2013 | Stiles, Conway, Karpinski, Sacco | Atlantic 10 Conference Championships |
| 3:01.40 | Feb. 20, 2010 | Howard, Ziegler, Sacco, Moliere | Atlantic 10 Championships |
| 3:03.49 | Feb. 21, 2009 | Atlantic 10 Championships - Day Four - Finals | |
| 3:08.85 | Nov. 21, 2008 | Terrier Invitational | |
| 3:12.72 | Oct. 18, 2008 | Massachusetts @Boston University |
