| Time | Date | Name | Meet |
|---|---|---|---|
| 1:39.95 | March 2, 2024 | Hunter Gubeno | Big XII Conference Championships |
| 1:40.96 | March 5, 2021 | Blake Hanna | Louisville Mens Invite- |
| 1:41.92 | Feb. 27, 2021 | Blake Hanna | American Athletic Conference Championships |
| 1:43.37 | Feb. 22, 2020 | Blake Hanna | American Athletic Conference Championships |
| 1:43.93 | March 2, 2019 | Blake Hanna | American Athletic Conference Championships |
| 1:46.21 | Dec. 1, 2018 | Connor Blatt | Miami University Invitational |
| 1:46.56 | Feb. 20, 2016 | Matt McDonald | American Conference Championships |
| 1:47.25 | March 2, 2013 | Joe Scherpenberg | Big East Conference Championships |
| 1:49.18 | Nov. 22, 2009 | Jeremy Peter | Hoosierland Invitational - College Results Only |
| 1:51.65 | Feb. 21, 2009 | Nicholas Saul | Big East Championships - Day Four - Finals |
| 1:51.88 | Nov. 15, 2008 | Jeremy Peter | Pittsburgh @Cincinnati |
| 1:56.97 | Nov. 7, 2008 | Nicholas Saul | Cincinnati @Ohio State |
