| Time | Date | Name | Meet |
|---|---|---|---|
| 43.65 | Feb. 11, 2023 | Ahmed Sallam | Metro Atlantic Athletic Conference Championships |
| 44.04 | Feb. 12, 2022 | Ahmed Sallam | Metro Atlantic Athletic Conference Championships |
| 44.44 | March 3, 2019 | Daniel Knoll | Eastern College Athletic Conference Championships |
| 44.63 | Feb. 16, 2019 | Daniel Knoll | Metro Atlantic Athletic Conference Championships |
| 44.95 | Feb. 17, 2018 | Daniel Knoll | Metro Atlantic Athletic Conference Championships |
| 45.49 | Feb. 14, 2015 | John Spitzer | Metro Atlantic Athletic Conference Championships |
| 45.56 | March 2, 2014 | John Spitzer | Eastern College Athletic Conference Championships |
| 45.93 | Feb. 15, 2014 | John Spitzer | Metro Atlantic Athletic Conference Championships |
| 46.22 | Feb. 16, 2013 | John Spitzer | Metro Atlantic Athletic Conference Championships |
| 46.45 | Feb. 26, 2012 | Nick Spinella | Eastern College Athletic Conference Championships |
| 46.64 | Feb. 27, 2011 | Alexander Lombardi | Eastern College Athletic Conference Championships |
| 46.65 | Feb. 14, 2009 | Keith Miller | Metro Atlantic Athletic Conference Championships - Day Three - Finals |
| 47.24 | Dec. 5, 2008 | Keith Miller | H2ounds Invitational |
