| Time | Date | Name | Meet |
|---|---|---|---|
| 3:47.10 | Feb. 18, 2022 | Spencer Sehlhorst | American Athletic Conference Championships |
| 3:48.42 | Feb. 21, 2020 | Spencer Sehlhorst | American Athletic Conference Championships |
| 3:49.08 | Feb. 20, 2015 | Ryan DePietro | American Conference Championships |
| 3:53.11 | Feb. 20, 2009 | Kuba Carda | Big East Championships - Day Three - Finals |
| 4:01.21 | Jan. 9, 2009 | Kuba Carda | Cincinnati @ Louisville |
