| Name | Time | Date | Meet |
|---|---|---|---|
| MacKenzie Roach | 4:31.32 | Feb. 9, 2024 | Southern Athletic Association Championships |
| Carly Good | 4:31.85 | Feb. 12, 2016 | 2016 Southern Athletic Association Championships |
| Susanna Kirby | 4:33.43 | Feb. 15, 2013 | 2013 Southern Athletic Association Championships |
| Susanna Kirby | 4:37.73 | Feb. 17, 2012 | Southern Collegiate Athletic Conference Championships |
| Susanna Kirby | 4:37.77 | Feb. 19, 2010 | Southern Collegiate Athletic Conference Championships |
| Susanna Kirby | 4:43.33 | Dec. 5, 2009 | DePauw Invitational |
| Hannah Emery | 4:51.55 | Jan. 17, 2009 | Washington University Invitational |
| Lynn Swiger | 5:14.41 | Dec. 5, 2008 | 2008 DePauw Invitational |
