| Name | Time | Date | Meet |
|---|---|---|---|
| Katie Smith | 22.25 | Feb. 25, 2017 | Boiler-Make-It Qualification C |
| Amywren Miller | 22.30 | March 18, 2010 | 2010 NCAA Division I Womens Championships |
| Amywren Miller | 22.37 | Feb. 19, 2009 | 2009 Big East Championships - Day Two - Finals |
| Amywren Miller | 23.02 | Oct. 31, 2008 | Pittsburgh @Notre Dame |
| Rebecca Grove | 23.38 | March 8, 2007 | 2007 NCAA Division I Womens Championships |
| Rebecca Grove | 23.48 | Nov. 18, 2005 | 2005 Minnesota Invitational |
