| Name | Time | Date | Meet |
|---|---|---|---|
| Raphael GRAND'PIERRE | 49.67 | Feb. 24, 2024 | NESCAC Mens Championships |
| Julian Abaldo | 49.76 | Feb. 24, 2018 | NESCAC Championships Men |
| Logan House | 50.29 | Feb. 22, 2014 | 2014 NESCAC Men's Championships |
| Peter Routh | 50.36 | Feb. 25, 2012 | New England Small College Athletic Conference Men's Championships |
| Mac Routh | 50.44 | Feb. 26, 2010 | New England Small College Athletic Conference (M) Championships |
| Roger Burleigh | 51.79 | March 17, 2006 | 2006 NCAA Division III Mens Championships |
| Roger Burleigh | 54.84 | Jan. 20, 2006 | 2006 ME Ground Hog International |
