| Name | Time | Date | Meet |
|---|---|---|---|
| Paris Zhang | 25.42 | Feb. 27, 2019 | American Athletic Conference Championships |
| Kayla Alf-Huynh | 25.51 | Feb. 23, 2011 | Conference USA Championships |
| Kayla Alf-Huynh | 25.97 | Nov. 19, 2010 | Phill Hansel Cougar Classic Invitational |
| Kayla Alf-Huynh | 27.22 | Nov. 13, 2010 | Tulane vs. Florida International |
| Lauren Pfohl | 27.64 | Feb. 24, 2010 | Conference USA Championships |
| Kayla Alf-Huynh | 27.81 | Nov. 21, 2009 | Houston Invitational |
| Grace Tarka | 33.09 | Oct. 3, 2009 | Tulane vs. New Orleans |
