| Name | Time | Date | Meet |
|---|---|---|---|
| Kate Augustyn | 4:19.79 | Feb. 18, 2023 | New England Womens and Mens Athletics Conference Championships |
| Kate Augustyn | 4:23.55 | Feb. 19, 2022 | New England Womens and Mens Athletics Conference Championships |
| Kate Augustyn | 4:25.88 | Dec. 4, 2021 | MIT Invitational |
| Katharine Pan | 4:27.50 | Dec. 3, 2016 | MIT Invitational |
| Joanna Han | 4:28.71 | Feb. 21, 2015 | 2015 New England Womens and Mens Athletics Conference Championships |
| Katelyn Rossick | 4:29.45 | Feb. 19, 2011 | New England Womens and Mens Athletics Conference Womens Championships |
| Katelyn Rossick | 4:33.37 | Dec. 4, 2010 | MIT Invitational |
| Nicole O'Keeffe | 4:41.87 | March 10, 2006 | 2006 NCAA Division III Womens Championships |
