| Event | Time | Date | Name | Meet | History |
|---|---|---|---|---|---|
| 50 Free | 19.90 | March 15, 1999 | Aaron Cole | NCAA Division III Men's Championship | |
| 100 Free | 43.81 | March 21, 2009 | John Geissinger | NCAA Division III Championships | |
| 200 Free | 1:37.20 | March 19, 2009 | David Curtis | NCAA Division III Championships | |
| 500 Free | 4:21.79 | March 21, 2012 | Al Weik | NCAA Division III Championships | |
| 1000 Free | 9:12.75 | March 7, 2021 | Sam Myaard | Denison vs. Ohio Wesleyan | |
| 1650 Free | 15:04.85 | March 24, 2012 | Al Weik | NCAA Division III Championships | |
| 50 Back | 22.03 | March 16, 2022 | Liam Picozzi | NCAA Division III Championship | |
| 100 Back | 47.56 | March 22, 2012 | Robert Barry | NCAA Division III Championships | |
| 200 Back | 1:44.93 | March 23, 2019 | Bebe Wang | NCAA Division III Championships | |
| 50 Breast | 25.32 | Jan. 28, 2023 | Elijah Venos | Denison vs. Ohio Wesleyan vs. Youngstown State | |
| 100 Breast | 53.13 | March 22, 2024 | Elijah Venos | NCAA Division III Championship | |
| 200 Breast | 1:57.75 | March 18, 2023 | Richie Kurlich | NCAA Division III Championship | |
| 50 Fly | 21.72 | March 7, 2021 | Ethan Russell Smith | Denison vs. Ohio Wesleyan | |
| 100 Fly | 47.43 | March 15, 2000 | Aaron Cole | NCAA Division III Men's Championship | |
| 200 Fly | 1:45.62 | March 22, 2019 | Mitch Williams | NCAA Division III Championships | |
| 100 IM | 48.99 | Feb. 11, 2023 | Richie Kurlich | North Coast Athletic Conference Championships | |
| 200 IM | 1:46.00 | March 16, 2016 | Jack Lindell | NCAA Division III Championships | |
| 400 IM | 3:47.31 | March 16, 2017 | Jack Lindell | NCAA Division III Championships | |
| 200 Free Relay | 1:18.78 | Feb. 13, 2020 | Picozzi, Senior, Ike, McHugh | North Coast Athletic Conference Championships | |
| 400 Free Relay | 2:56.23 | Feb. 12, 2022 | Daly, Ike, Verstandig, Picozzi | North Coast Athletic Conference Championships | |
| 800 Free Relay | 6:29.59 | March 23, 2018 | Horton, Hohm, Wang, Stevenson | NCAA Division III Championships | |
| 200 Medley Relay | 1:27.73 | March 16, 2022 | Picozzi, Houskeeper, Kurlich, Ike | NCAA Division III Championship | |
| 400 Medley Relay | 3:13.27 | March 17, 2022 | Picozzi, Houskeeper, Kurlich, Ike | NCAA Division III Championship |
